A kind of Chiral Zinc Complexes with nitrogen and its synthesis method, namely an alpha isobutyl -1- six hydrogen pyridine pnp5 zinc complexes, characterized in that: as shown by the following chemical formula of the complexes of alpha isobutyl -1- six hydrogen pyridine and triethylamine two hydrated zinc chloride preparation and synthesis method of the complexes by six hydrogen pyridine propanenitrile and D- leucinol in anhydrous anaerobic conditions and catalyst ZnCl2 in presence of a large excess of anhydrous chlorobenzene solvent refluxing for 24 hours, then isolated and purified, namely after the reaction from chlorobenzene, dissolved in water after extraction with chloroform, extraction of precipitate after purification by column chromatography; complexes (I) with petroleum ether and dichloromethane eluent, column chromatography, natural volatile complexes of single crystal. The complexes show a certain catalytic activity in the nitrile silicification reaction of benzaldehyde, with a yield of 64%.
【技术实现步骤摘要】
本专利技术涉及一种金属有机配位化合物(配合物)及其制备方法，特别涉及含氮的手性金属有机配合物及其制备方法，确切地说是一种手性锌氮配合物及其合成方法。二、
技术介绍
随着有机化学的发展，金属有机化合物在有机合成中的应用愈来愈广，是现在有机化学中极为活跃的领域之一，已经广泛应用于有机合成反应中。20世纪60年代后期出现的使用手性配体与过渡金属络合物催化的不对称合成反应大大加速了手性药物的研究。 化学催化不对称合成法的重要内容便是手性配体及含金属催化剂的设计，从而使反应具有高效和高对映选择性。近年来手性锌氮金属配合物在不对称催化领域取得了较好的催化效^ ο参考文献1. Michaels,Heather Α. ；Murphy,Christopher S. ；Clark,Ronald J. ；Davidson, Michael W. ；Zhu, Lei.Inorganic Chemistry(2010),49(9),4278-4287.2. . Mei, Luo ；Ming,Tang Hai ；Rong,Li Qian；Jie,Sun ；Zhong,Yang Shan ；Liang, Li Xue. Journal of Chemical Sciences(Bangalore, India)(2009),121(4), 435-440.3. Dong, Qingchen ；Ma, Xiaping ；Guo,Jianping ；Wei,Xuehong ；Zhou, Meisu ；Liu, Diansheng. Inorganic Chemistry Communi...
【技术保护点】
１．一种手性锌氮配合物，即一种α－－异丁基－１－六氢吡啶基乙胺氯化锌配合物，其特征在于：α－－异丙基－１－六氢吡啶基乙胺与无水氯化锌制备的、由以下化学式所示的配合物：
【技术特征摘要】
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