The invention relates to a preparation method of a recombinant human endostatin thermosensitive thermosensitive chitosan gel for injection, which comprises chitosan and recombinant human vascular endostatin. The temperature sensitive chitosan gel prepared by physical gel method, namely chitosan adding hydrochloric acid solution, stirring until completely dissolved in a water bath; the injection of recombinant human endostatin buffer soluble chitosan in hydrochloric acid solution; the control of water temperature, stirring continuously under the condition of adding biocompatibility the auxiliary; stop stirring, regulating water bath temperature, static. When the solution is converted to a non flowing semi-solid or solid, a chitosan hydrogel is obtained from a human group of endostatin.
【技术实现步骤摘要】
【技术保护点】
１． 一种制备血管内皮抑制素壳聚糖温度敏感型凝胶的方法，其特征在于：（１） 将壳聚糖酸性溶液与血管内皮抑制素混合；（２） 搅拌的条件下加入生物相容性的助剂；（３） 停止搅拌，调节反应体系温度，静置得血管内皮抑制素的壳聚糖凝胶。
【技术特征摘要】
【专利技术属性】
技术研发人员：许向阳，李玲，王青松，刘春晖，
申请(专利权)人：江苏先声药物研究有限公司，
类型：发明
国别省市：84
还没有人留言评论。发表了对其他浏览者有用的留言会获得科技券。