一种伊维菌素混合胶束注射剂及其制备方法技术

本发明专利技术提供一种减少驱杀家畜寄生虫时发生中毒以及局部反应几率的伊维菌素混合胶束注射剂及制备方法。所述胶束注射剂以伊维菌素作为活性成分，采用胆盐/磷脂混合胶束系统制成注射剂，其不仅有效地解决了伊维菌素难溶于水的问题，还极大提高了胶束注射剂的载药量。本发明专利技术制备的混合胶束注射剂，制备工艺简单，同时可降低驱杀家畜寄生虫时发生毒副反应的几率。

A kind of mixed micelles of Ivermectin Injection and preparation method thereof

The invention provides a poisoning and local reaction probabilities of mixed micelles of Ivermectin Injection and a preparation method thereof to reduce flooding kill livestock parasites. The micelle injection with ivermectin as active ingredient, the bile salt phosphatidylcholine mixed micelles system into injection, which not only solves the problem of ivermectin is difficult to dissolve in water, but also greatly improved the drug loading micelles injection. The mixed micelle injection prepared by the invention has the advantages of simple preparation process and low toxic and side reaction rate when expelling livestock parasites.

【技术实现步骤摘要】

【技术保护点】
１．一种伊维菌素混合胶束注射剂，其特征在于主要由基于重量份计的伊维菌素１份，胆盐２～１２份、磷脂１．２～６份和适量的注射溶剂制成。

【技术特征摘要】

【专利技术属性】
技术研发人员：龚照墉，刘振谧，
申请(专利权)人：成都师创生物医药科技有限公司，
类型：发明
国别省市：90