一种多羟基长链脂肪酸及其分离提取方法和在抑制芳香化酶活性中的应用技术

本发明专利技术公开了一种多羟基长链脂肪酸，即如式１所示的化合物１０，１１，１２－三羟基十七碳二烯酸，以及它的分离提取方法。本发明专利技术的化合物未见报道，且其具有较强的芳香化酶抑制活性。本发明专利技术还公开了这种多羟基长链脂肪酸或含其的植物提取物在制备抑制芳香化酶活性的制剂中的应用和在制备预防和治疗前列腺增生疾病的药物组合物中的应用。

Polyhydroxy long chain fatty acid, method for separating and extracting and its application in inhibiting aromatase activity

The invention discloses a polyhydroxy long-chain fatty acid, as shown in Formula 1 compounds 10, 11, 12 - three hydroxy seventeen carbon two acid, and its extraction method. The compounds of the present invention have not been reported and have strong aromatase inhibitory activity. Application of the present invention also discloses the preparation of polyhydroxy long-chain fatty acids or plant extracts containing the preparation of aromatase inhibition in the preparation and pharmaceutical compositions for prevention and treatment of prostatic hyperplasia in preparation of.

【技术实现步骤摘要】

【技术保护点】
一种如式１所示的多羟基长链脂肪酸，即１０，１１，１２－三羟基十七碳二烯酸。　＊＊＊　式１。

【技术特征摘要】

【专利技术属性】
技术研发人员：杨义芳，李永辉，李坤，杨念云，
申请(专利权)人：上海医药工业研究院，
类型：发明
国别省市：31[中国|上海]