The present invention provides a substituted pyrroliane compound and pharmaceutical composition and its application, and the pyrroliane compound is a compound shown in the formula (1), or its polycrystalline form, pharmaceutically acceptable salts, prodrugs, stereoisomers, isotopic variants, hydrates or solvent compounds. The compound can be suppressed as a hepatitis C virus inhibitor, and has a better inhibitory activity of the hepatitis C virus protein NS5A, and a better pharmacodynamic / pharmacokinetic performance, and can be used for the preparation of a drug for the treatment of hepatitis C virus infection.
【技术实现步骤摘要】
【国外来华专利技术】PCT国内申请,说明书已公开。
【技术保护点】
PCT国内申请,权利要求书已公开。
【技术特征摘要】
【国外来华专利技术】2016.05....
【专利技术属性】
技术研发人员:王义汉,赵九洋,
申请(专利权)人:深圳市塔吉瑞生物医药有限公司,
类型:发明
国别省市:广东,44
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