作为盐皮质激素受体拮抗剂的并环类化合物制造技术

本发明专利技术属于医药技术领域，具体涉及通式(I)所示的作为盐皮质激素受体拮抗剂的并环类化合物、其药学上可接受的盐及其异构体，这些化合物的制备方法，含有这些化合物的药物制剂，以及这些化合物、其药学上可接受的盐或其异构体在制备治疗和/或预防肾损伤、心血管疾病如高血压、和/或内分泌疾病的药物中的应用，其中X、Y1、Y2、Y3、R1、R2a、R2b、R3a、R3b、R4、Cy和n如说明书中所定义。

Cyclic compounds as antagonists of mineralocorticoid receptors

The invention belongs to the technical field of medicine, in particular to the general formula (I) is shown as a mineralocorticoid receptor antagonist and ring like salt and its isomers, pharmaceutically acceptable compounds, methods of preparing such compounds, pharmaceutical preparations containing these compounds, and the application of these drug compounds, pharmaceutically acceptable salt or its isomer preparation treatment and / or prevention of cardiovascular diseases, such as hypertension, renal injury and / or endocrine diseases in the system in which X, Y2, Y1, R1, R2a, Y3, R2b, R3a, R3b, Cy, R4, and N are as defined in the specification.

【技术实现步骤摘要】
【国外来华专利技术】

【技术保护点】

【技术特征摘要】
【国外来华专利技术】...

【专利技术属性】
技术研发人员：黄振华，王金远，张德东，
申请(专利权)人：山东亨利医药科技有限责任公司，
类型：
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