水黄皮黄酮类成分的提取纯化工艺制造技术

一种水黄皮黄酮类成分的提取纯化工艺，其提取步骤为：①取水黄皮根、茎、叶粗粉，按药材重量８～１５倍的比例（质量体积比）加入５０～７０％乙醇溶液，于６０～８０℃回流提取３次，每次０．５～２．０ｈ，合并提取液，滤过，减压回收乙醇，得水黄皮药材提取液；②将步骤①得到的水黄皮药材提取液静置，取上清液应用大孔吸附树脂进行纯化，乙醇洗脱；③收集步骤②的乙醇洗脱液，减压回收乙醇浓缩，５０～６５℃真空干燥，得提取物纯化产品。本发明专利技术的水黄皮药材提取物产品中总黄酮质量含量为５０％～７０％，其水黄皮总黄酮转移率为７５～８０％。与现有技术相比，本发明专利技术具有工艺简化，活性成分损失减少，安全性较高等优点。

Extraction and purification process of Flavonoids from water orange

A process for extracting and purifying Pongamia pinnata flavonoids, the extraction steps are as follows: the water yellow root and stem and leaf meal, according to the weight of the medicine for 8 to 15 times (the ratio of mass to volume ratio) with 50 ~ 70% ethanol at 60 to 80 DEG C, extracting 3 times, every time 0.5 ~ 2.0h. Combined extraction, filtration, vacuum recovery of ethanol, water extract of the Yellow medicine; Pongamia crude aqueous extract of step 1 get static, the supernatant was purified by macroporous adsorption resin elution; the collection procedure of ethanol elution liquid, ethanol concentration vacuum recovery of 50 ~ 65 DEG C, vacuum dry extract purification products. The total flavone content of the product extracted from the aqueous extract of Chinese medicinal herbs is from 50% to 70%, and the total flavone transfer rate of the water bamboo yellow is 75 to 80%. Compared with the prior art, the invention has the advantages of simple process, less loss of active components, high safety, etc..

【技术实现步骤摘要】

【技术保护点】
１．一种水黄皮药材提取物，其特征是所述提取物中总黄酮质量含量为５０～７０％。

【技术特征摘要】

【专利技术属性】
技术研发人员：朱毅，赵映淑，
申请(专利权)人：朱毅，
类型：发明
国别省市：66[中国|海南]