硝苯地平渗透泵型控释片制造技术

技术编号:6049400 阅读:326 留言:0更新日期:2012-04-11 18:40
本发明专利技术提供了一种硝苯地平渗透泵型控释片,采用乙基纤维素-聚维酮作为半透膜材料,长期储存半透膜不老化,末端释放不降低;优选采用不对称外形,不仅降低末端释放残留,还可简化激光打孔的识别,并且在传送带上输送时平稳放置,激光打孔时孔较易打在正中间,更有利于药品平稳释放。本发明专利技术还提供了一种改善硝苯地平渗透泵型控释片抗老化性能的方法,其特征是采用乙基纤维素-聚维酮作为半透膜材料。此外,本发明专利技术还提供了乙基纤维素-聚维酮组合物用于制备具有抗老化性能的硝苯地平渗透泵型控释片的用途。

Nifedipine osmotic pump controlled release tablets

The invention provides a nifedipine osmotic pump controlled-release tablets, using ethyl cellulose povidone as membrane material, long-term storage of semipermeable membrane aging, end release does not reduce the asymmetric shape; preferably, not only reduce the release of terminal residues, but also simplify the identification of laser drilling, and the conveying belt in the smooth place laser drilling hole, is easy to play in the middle, more conducive to stable drug release. The invention also provides a method to improve the nifedipine osmotic pump controlled-release tablets were anti aging, which is characterized by the use of ethyl cellulose povidone as membrane materials. In addition, the present invention also provides the use of ethyl cellulose povidone compositions for the preparation of nifedipine osmotic pump controlled release tablets with anti-aging properties.

【技术实现步骤摘要】

【技术保护点】
1.一种硝苯地平渗透泵型控释片,其特征是采用乙基纤维素-聚维酮作为半透膜材料,乙基纤维素-聚维酮的重量比为30∶14~18。

【技术特征摘要】
...

【专利技术属性】
技术研发人员:姜庆伟衣伟锋
申请(专利权)人:北京天衡药物研究院
类型:发明
国别省市:11

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