The invention discloses a method for increasing the yield of an antibacterial substance A21978C. The invention of Streptomyces roseosporus (Streptomyces roseosporus) to join the red yeast fermentation in the production process of A21978C (Rhodotorula sp.) were cultured in A21978C to improve the yield of mixed bacteria. According to the present invention, the yield of A21978C in the metabolite can be significantly increased, thereby providing a completely new way for the fermentation production of A21978C.
【技术实现步骤摘要】
【技术保护点】
一种提高抗菌物质A21978C产量的方法,其特征在于,在玫瑰孢链霉菌(Streptomyces roseosporus)发酵生产A21978C过程中加入红酵母菌(Rhodotorula sp.)进行混菌培养。
【技术特征摘要】
【专利技术属性】
技术研发人员:齐晓丹,戈梅,金一平,陈代杰,罗敏玉,夏兴,阮丽军,杨天,殷瑜,
申请(专利权)人:上海来益生物药物研究开发中心有限责任公司,浙江医药股份有限公司新昌制药厂,
类型:发明
国别省市:31[中国|上海]
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