The invention discloses a docetaxel lipid preparation and a preparation method thereof. The docetaxel lipid preparation of the invention comprises the following components: docetaxel, polyethylene glycol - twelve hydroxy stearic acid ester and phospholipid. Docetaxel liposome preparation provided by the invention improves the docetaxel preparation safety and compliance, the preparation can be diluted with spontaneous emulsification to form nanoparticles for intravenous injection, the increase of docetaxel in vivo absorption, and can achieve the purpose of tumor targeting. The preparation process of the invention is simple and convenient, and is suitable for industrial production.
【技术实现步骤摘要】
【技术保护点】
一种多烯紫杉醇脂质制剂,包括如下组分:多烯紫杉醇、聚乙二醇-十二羟基硬脂酸酯和磷脂;所述磷脂中磷脂酰胆碱含量大于80%。
【技术特征摘要】
【专利技术属性】
技术研发人员:张小宁,郝艳丽,邰文,邬月明,王晚,
申请(专利权)人:清华大学,
类型:发明
国别省市:11[中国|北京]
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