对分隔长片段序列进行组装的方法和装置制造方法及图纸

本发明专利技术涉及对分隔长片段序列进行组装的方法、装置和系统。一种对分隔长片段序列进行组装的方法，包括：(a)通过测序获得读段集，并记录所述读段集中的读段对应的测序孔，一个测序孔包含至少一条长片段序列；(b)利用所述读段及所述读段对应的测序孔，对多个种子序列进行并行延伸，以获得多个序列重叠群，所述多个种子序列通过已知序列确定；(c)基于所述读段、所述序列重叠群以及所述序列重叠群包含的读段对应的测序孔，构建骨架序列，以获得分隔长片段序列的组装结果。

Method and device for assembling long fragment segments

The invention relates to a method, device and system for assembling a long fragment sequence. A method of assembling a sequence of separated long segments, including: (a) obtaining a reading segment by sequencing and recording the sequence holes corresponding to the reading segment of the read segment, and a sequencing hole containing at least one long fragment sequence; (b) parallel continuation of the multiple seed sequences using the read segment and the sequence holes corresponding to the read segment. To obtain multiple sequence overlapping groups, the multiple seed sequences are determined by the known sequence; (c) the sequence of the skeleton is constructed based on the reading segment, the sequence overlapping group, and the sequence holes corresponding to the reading segments included by the sequence overlapping groups to obtain the assembly results of the long segment sequence.

【技术实现步骤摘要】
【国外来华专利技术】PCT国内申请，说明书已公开。

【技术保护点】
PCT国内申请，权利要求书已公开。

【技术特征摘要】
【国外来华专利技术】PCT国内申请，...

【专利技术属性】
技术研发人员：谢寅龙，黄伟华，李净净，郭瑞东，唐静波，邓超，
申请(专利权)人：深圳华大生命科学研究院，
类型：发明
国别省市：广东,44