无糖型川贝罗汉止咳颗粒剂的制备方法技术

一种无糖型川贝罗汉止咳颗粒剂的制备方法，首先对中药进行干燥处理，粗粉碎，川贝母用气流式粉碎，罗汉果、枇杷叶和桔梗用半仿生提取+醇提法或半仿生提取法或醇提+水提法浸提制备清膏，然后加入川贝母粉、薄荷脑和辅料以常规方法制备止咳颗粒剂，它克服了传统颗粒中药制剂以蔗糖作为矫味剂而分解某些药物有效成分和吸收的问题，能满足各类人群服用中药制剂的需要。特别适用于糖尿病、高血糖、高血压和肥胖等症的患者的服用。本方法将中药粗粉碎后，在提取工艺中与溶媒的接触面积增加，提取时间短，转移率高，既节约时间，加快了生产周期，还提高原料的利用率，并保持原药的有效成分。

Method for preparing sugarless granules Lohan Chuanbei cough

A method for preparing sugar free type fritillary Lohan cough granules, the first drying treatment of traditional Chinese medicine, coarse crushing, Chuanbeimu airflow pulverization, mangosteen, loquat leaf and Platycodon root extraction + water extraction extraction ointment by semi bionic extraction + alcohol extraction and semi bionic extraction or alcohol, then add Sichuan Fritillaria powder, menthol and excipients with conventional methods for preparing cough granules, which overcomes the disadvantages of traditional Chinese medicine granules with sucrose as correctant and decomposition of effective components of certain drugs and absorption problems, to meet the various needs of people who use traditional Chinese medicine preparation. Especially for diabetics, hyperglycemia, hypertension and obesity. The method of traditional Chinese medicine after coarse crushing, the contact area with the solvent in the extraction process, short extraction time, high transfer rate, saving time, speeding up the production cycle, but also improve the utilization rate of raw materials, ingredients and keep the original.

【技术实现步骤摘要】

【技术保护点】
１．一种无糖型川贝罗汉止咳颗粒剂的制备方法，其特征在于：包括先对各中药进行干燥处理，粗粉碎后用气流式粉碎机进行粉碎，川贝母粗粉碎备用，罗汉果、枇杷叶和桔梗用半仿生提取＋醇提法或半仿生提取法或醇提＋水提法浸提制备清膏，提取清膏以后也可以将清膏减压干燥，粉碎得药物提取物干粉，然后加入川贝母粉、薄荷脑和辅料以常规方法制备止咳颗粒剂，包括由以下配比的中药成分和重量份数：川贝母２５～６０份，罗汉果８～２５份，枇杷叶３００～５００份，桔梗８０～２５０份，薄荷脑０．２～１．２份，药用辅料和药用溶剂适量。

【技术特征摘要】

【专利技术属性】
技术研发人员：黄大权，
申请(专利权)人：广西健丰药业有限公司，
类型：发明
国别省市：45