The invention discloses a double salt osmotic pump barnidipine or physiologically acceptable controlled-release pharmaceutical composition, it comprises a double tablet core and coating, pharmaceutical excipients double-layer tablet core contains effective dose of barnidipine or physiologically acceptable salts and pharmaceutically acceptable coating. The film is a semi permeable membrane containing hole making agent. Double salt osmotic pump prepared by the invention of barnidipine or physiologically acceptable controlled-release drug composition, can effectively control the drug release in a certain period of time, reduce the frequency of administration, the blood concentration in vivo is stable, so as to ensure patient medication during blood concentration in vivo is stable and effective, and fundamentally improve the adaptation of the safety and efficacy of drugs and patients.
【技术实现步骤摘要】
【技术保护点】
一种含有巴尼地平或其生理上可接受的盐双层渗透泵控释药物组合物,其结构为双层片芯外包包衣膜,所述双层片芯由含药层和助推层组成,双层片芯外包有包衣膜,包衣膜在含药层一侧有一个释药小孔。
【技术特征摘要】
【专利技术属性】
技术研发人员:林鹏,李育巧,郑顺利,
申请(专利权)人:北京科信必成医药科技发展有限公司,
类型:发明
国别省市:11[中国|北京]
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