治疗心脑血管病症的中药滴丸剂及其制备方法技术

技术编号:4172637 阅读:344 留言:0更新日期:2012-04-11 18:40
本发明专利技术公开了一种活血化瘀、通窍止痛、扩张血管、增加冠状动脉血流量,用于冠心病,心绞痛及脑动脉硬化症的中药组合物的新剂型及其制法。该中药滴丸剂的制备方法为:除鹿心粉外,川芎、红花、泽泻、牛膝、郁金、远志、九节菖蒲、酸枣仁、甘草粉碎至150目,备用。其余丹参、赤芍、制何首乌、枸杞子、葛根、地龙等6味,采用动态逆流提取方法加4倍量水煎煮2小时,滤过,滤液浓缩成稠膏。将上述稠膏、药物细粉和鹿心粉,按照4∶7的比例加入熔融的聚乙二醇4000中,混合均匀,70℃保温,等速滴入12℃~15℃的液体石蜡中,将成形的滴丸沥尽并擦除液体石蜡,即得。试验证明该中药滴丸剂比原来胶囊剂的疗效和生物利用度都有显著性提高。

Chinese medicine drop pill for treating cardiovascular and cerebrovascular diseases and preparation method thereof

The invention discloses a method for promoting blood circulation, relieving pain, Tongqiao dilation of blood vessels, increase blood flow of coronary artery, for coronary heart disease, angina pectoris and traditional Chinese medicine composition of cerebral arteriosclerosis and preparation method thereof. The preparation method for the traditional Chinese medicine pill: except the deer heart powder, chuanxiong, safflower, Alisma, Achyranthes, radix curcumae, Radix Polygalae, nine rhizome, jujube kernel, licorice crushed to 150 meshes, standby. The remaining Salvia miltiorrhiza, red peony root, Radix Polygoni Multiflori, Fructus Lycii, Ge Gen, earthworm and other 6 flavor, the use of dynamic countercurrent extraction method, plus 4 times the amount of water for 2 hours, filtration, filtrate concentrated into thick paste. The thick paste, drug powder and deer heart powder according to the ratio of 7 polyethylene glycol 4 into melted in 4000, mixed, 70 DEG C, isokinetic instillation of liquid paraffin 12 to 15 DEG C, forming and erasing pills Lek liquid paraffin, i.e.. The experiment proved that the curative effect and bioavailability of the traditional Chinese medicine drop pills were significantly higher than those of the original capsules.

【技术实现步骤摘要】

【技术保护点】
用于心脑血管病症的中药滴丸剂,其特征在于该滴丸剂的制备方法为: 步骤1:称取丹参4~80重量份、赤芍3~60重量份、制何首乌3~6重量份、枸杞子3~60重量份、葛根3~60重量份、川芎3~60重量份、红花2~40重量份、泽泻3~60重 量份、牛膝3~60重量份、地龙3~60重量份、郁金0.3~6重量份、远志(蜜炙)3~60重量份、九节菖蒲3~60重量份、酸枣仁(炒)2~40重量份、鹿心粉3~60重量份、甘草2~40重量份; 步骤2:将川芎、红花、泽泻、牛膝、郁金、远 志、九节菖蒲、酸枣仁、甘草粉碎成细粉,过筛,得药物粉碎粉; 步骤3:丹参、赤芍、何首乌、枸杞子、葛根、地龙加水煎煮,滤过,滤液浓缩至稠膏; 步骤4:将步骤2所得药物粉碎粉、步骤3所得稠膏及鹿心粉,加入熔融的基质中,混合均匀,保温 ,等速滴入冷凝液体中,将成形的滴丸沥尽并擦除冷凝液,即得。

【技术特征摘要】

【专利技术属性】
技术研发人员:付立家付建家
申请(专利权)人:北京亚东生物制药有限公司
类型:发明
国别省市:11[中国|北京]

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