一种检测左眼等效球镜的SNP位点及其应用制造技术

本发明专利技术属于生物医学、基因检测技术领域，具体涉及一种检测左眼等效球镜的SNP位点及其应用。具体地，所述SNP位点包括rs146160422、rs75054661、rs4959012、rs757262、rs757259、rs145293869、rs34649612、rs7157977、rs563363438、rs2277533、rs7258847、rs78661674、rs5845912、rs8137790。rs8137790。rs8137790。

A SNP site for detecting left eye equivalent spherical mirror and its application

【技术实现步骤摘要】
一种检测左眼等效球镜的SNP位点及其应用


[0001]本专利技术属于生物医学、基因检测
，具体涉及一种检测左眼等效球镜的SNP位点及其应用。

技术介绍

[0002]眼科疾病是指发生在眼部区域的疾病，常见眼科疾病有近视、散光、白内障、青光眼、中心浆液性视网膜病变、干眼症、交感性眼炎、夜盲症、弱视、沙眼、糖尿病视网膜病变、结膜炎、老花眼、色盲、视网膜色素变性、视网膜中央动脉阻塞、视网膜脱落、远视、针眼、雪盲症、霰粒肿、飞蚊症等。在调节放松的状态下，平行光线经眼球屈光系统后聚焦在视网膜之前，称为近视。
[0003]屈光度是指屈光不正状态下所产生的度数大小，当屈光度发生时，一般多代表近视、散光、远视或是弱视等临床表现，近视、远视通常为球镜(S)，散光为柱镜(C)，目前采用等效球镜度数(Spherical Equivalent Refraction，SE)评价屈光度，等效球镜度数＝球镜度数+散光度数*1/2。屈光度≤
‑
0.50D可作为近视诊断的循证共识阈值。更具体地，近视的定义是当调节放松时，眼睛的等效球镜屈光不正≤...

【技术保护点】

【技术特征摘要】
1.一组左眼等效球镜相关的SNP位点组合，所述SNP位点组合包含rs146160422、rs75054661、rs4959012、rs757262、rs757259、rs145293869、rs34649612、rs7157977、rs563363438、rs2277533、rs7258847、rs78661674、rs5845912、rs8137790。2.如权利要求1所述的SNP位点组合，所述SNP位点组合是(1)rs146160422、rs1051097、rs12129653、rs17553619、rs2275856、rs150943357、rs117712357、rs192688643、rs75054661、rs2292661、rs186309103、rs11556167、rs9790356、rs9790628、rs7717970、rs12519352、rs11133847、rs2304068、rs4959012、rs757262、rs757259、rs929156、rs236444、rs17138865、rs17545405、rs148474510、rs8178175、rs55991828、rs12549018、rs529268660、rs145293869、rs1627784、rs200536689、rs573212、rs4745933、rs3751031、rs12811832、rs11168338、rs2306436、rs3741990、rs34649612、rs7157977、rs17646457、rs563363438、rs2277533、rs2452524、rs4904、rs77707876、rs370627229、rs9929443、rs149149128、rs144944402、rs113276760、rs17682036、rs59176398、rs732109、rs11260004、rs11882197、rs13535、rs2241356、rs57747888、rs397764300_rs58960485、rs16015、rs151309111、rs77561511、rs78422130、rs7258847、rs78661674、rs2183573、rs9981301、rs4624474、rs369859899、rs5845912、rs9628315、rs8138121、rs8137790；或，(2)rs28566954、rs377223831、rs41274480、rs146160422、rs12049046、rs16830693、rs1051097、rs12129487、rs111686948、rs12129653、rs7527057、rs144990398、rs17553619、rs140141416、rs17024525、rs117354680、rs3747626、rs16861256、rs7542316、rs7531786、rs2231241、rs2231240、rs10911390、rs10911391、rs10911392、rs12045762、rs16861394、rs6661715、rs13374714、rs13375853、rs2275856、rs6676149、rs3754234、rs2273584、rs6696123、rs11583387、rs3768066、rs3820553、rs1063128、rs3738521、rs3890478、rs28383065、rs6720415、rs6546511、rs150943357、rs77408734、rs117712357、rs3821036、rs192688643、rs6734083、rs68104327、rs35996697、rs151056400、rs116828761、rs28538922、rs138467334、rs2305613、rs115586700、rs76657333、rs79162067、rs75054661、rs4387990、rs117336796、rs77786095、rs2292661、rs12630803、rs3774765、rs1800766、rs56106326、rs139051035、rs7696197、rs80050773、rs10019009、rs61732380、rs17029087、rs3817083、rs10026790、rs11944752、rs3816873、rs2718684、rs12648093、rs186309103、rs11556167、rs9790356、rs9790628、rs4956981、rs13171103、rs4956987、rs7717970、rs12519352、rs11133847、rs117918201、rs56349002、rs2277042、rs6875303、rs6860528、rs25782、rs117977823、rs11959659、rs2304068、rs192194、rs147518598、rs74403861、rs3734056、rs139635794、rs1611212、rs28400887、rs9261424、rs4959012、rs757262、rs757259、rs929156、rs763046、rs236444、rs73733155、rs2100375、rs1051429、rs17181352、rs8191890、rs61236605、rs142944427、rs3735384、rs17138865、rs17545405、rs140518317、rs2214098、rs148474510、rs555905346、rs6945709、rs10240503、rs2074690、rs374377569、rs200506987、rs6996950、rs145988500、rs6558166、rs149587418、rs8178175、rs55991828、rs117571873、rs77428666、rs12549018、rs529268660、rs1815549、rs139669465、rs145293869、rs1627784、rs139212809、rs200536689、rs77023914、
rs573212、rs28369760、rs185006838、rs75361513、rs139...

【专利技术属性】
技术研发人员：王宏，徐良德，
申请(专利权)人：温州眼视光国际创新中心，
类型：发明
国别省市：