一种止血防粘连多肽水凝胶的制备方法技术

本发明专利技术提供了一种止血防粘连多肽水凝胶的制备方法，本发明专利技术多肽自组装水凝胶的凝血率高达99.11

【技术实现步骤摘要】
一种止血防粘连多肽水凝胶的制备方法


[0001]本专利技术涉及生物医药领域，特别涉及一种止血防粘连多肽水凝胶的制备方法。

技术介绍

[0002]传统的止血材料，如脱脂棉、纱布等经过灭菌后在创伤处进行压迫性止血，以使用历史长久、应用广泛、价格低廉以及使用方便等优点为人们所熟悉。但是，传统型止血材料只是对创面起简单的物理保护作用，在应对动脉大量出血的紧急情况时并不能起到及时控制出血量的作用，而且，脱脂棉以及纱布容易粘连创面，后期处理相对比较繁琐，同时会引起伤者的疼痛感。水凝胶是指水溶性聚合物分子间通过离子键、共价键、氢键等物理或化学方式交联形成三维网状结构的体系，具有强度可调、形状可塑以及可设计功能化的优点。根据不同应用水凝胶可以被制备成多种形式，包括平板、微粒、纳米颗粒、涂层和薄膜等。基于以上特性，水凝胶在食品、组织工程和医用敷料等诸多领域发挥关键作用。水凝胶敷料相比于传统敷料具有更优异的生物功能性，如与创面结合良好、保湿透气、方便更换、可吸收渗液以及可负载各类药物等诸多优点。有研究表明，湿性愈合己经被确立为各类迁移不愈的创面的理想治疗方式，保持本文档来自技高网...

【技术保护点】

【技术特征摘要】
1.一种止血防粘连多肽水凝胶，其特征在于，所述多肽自组装水凝胶的氨基酸选自
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His、
D
His
‑
D
His
‑
D
His
‑
D
His
‑
D
His
‑
D
His
‑
D
His
‑
D
His、
L
Arg
‑
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His、
L
His
‑
L
His
‑
L
His
‑
L
Arg
‑
L
His
‑
L
His
‑
L
His
‑
L
His、
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
His
‑
L
Arg、
L
Arg
‑
L
His
‑
L
His
‑
L
Arg
‑
L
His
‑
L
His

【专利技术属性】
技术研发人员：赵倩，江瑞辰，
申请(专利权)人：广州图微科创生物科技有限公司，
类型：发明
国别省市：