The invention belongs to the technical field of chemical aspects of bandages, dressings or absorption pads, and discloses a hemostatic drug for nephrectomy in animals. 3M tissue adhesive is a n-butyl cyanoacrylate adhesive, which can be used to bind tissues, protect wounds and stop bleeding in animals. It can be directly applied to the wound. Within seconds after contact with tissues or body fluids, the wound can be adhered and hemostasis. Good hemostasis effect can be achieved without compression, suture and electrocoagulation. In practice, it is found that the hemostasis time of the tissue glue after forming a protective film is long, and almost no bleeding in a short time is caused by shedding. Postoperative hemorrhage improved the success rate of the operation. Tissue glue was used to stop bleeding with a small amount of dosage, about 150 drops of 3ml 3M tissue glue in a bottle, while only 3 drops were needed for 2/3 nephrectomy of one side in a 200-g rat. Therefore, one bottle of tissue glue is expected to be used for 2/3 nephrectomy of one side in 50 200-g rats, which is economical and affordable.
【技术实现步骤摘要】
一种动物肾切除止血的药物
本专利技术属于绷带、敷料或吸收垫的化学方面
;或者绷带、敷料或吸收垫的材料应用
,尤其涉及一种动物肾切除止血的药物。
技术介绍
目前,业内常用的现有技术是这样的:近年来慢性肾病发病率在全国内外呈逐年上升趋势,我国成年人群中慢性肾病的发病率为10.8%(约1.2亿),继发性肾病患者伴随高血压、糖尿病、痛风、系统性红斑狼疮等发病率的提高,我国慢性肾病发病率及死亡率呈逐年增加。而慢性肾病的发病机制仍有待进一步研究。慢性肾病动物模型是最好的模拟人体内肾病发展过程的模型。目前最常用的模型是5/6肾切除术后动物模型。以往做肾切除术动物模型止血常用的手段有压迫止血、缝合止血、电凝刀止血,然而压迫止血无法达到彻底有效止血的效果,且压迫时间需要较长,开腹时间长常导致感染率升高;缝合止血虽比压迫止血效果稍好,但是由于动物肾脏比人肾脏小,且肾脏组织的质地脆弱,需要娴熟的操作技术,缝合止血实行起来仍有一定的难度;而电凝刀止血有操作简单、省时、经济等优点,但是电凝刀止血有明显的热效应,容易损伤周围组织,容易形成电损伤等缺点。综上所述,现有技术存在的问题 ...
【技术保护点】
1.一种动物肾切除止血的药物,其特征在于,所述动物肾切除止血的药物为3M组织胶。
【技术特征摘要】
1.一种动物肾切除止血的药物,其特征在于...
【专利技术属性】
技术研发人员:黄海燕,廖蕴华,李福记,叶旭东,李晓华,黄昱茗,赵赫,卢晶晶,潘永青,
申请(专利权)人:廖蕴华,
类型:发明
国别省市:广西,45
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