The invention discloses the use of Epimedium extract in the preparation of drugs for the treatment of brain nerve injury and cognitive impairment after radiation. The learning and memory of mice after radiation are obviously decreased. After the treatment of Epimedium extract, the learning and memory ability of mice is obviously improved, and the related protease PV, Ki67, DCX of the nerve fine. The enhanced expression of CB indicates that Epimedium does have the effect of preventing radiation on brain nerve damage. The damage of neurons will lead to cognitive impairment of animals. Epimedium, as a traditional Chinese medicine, has a good preventive and protective effect on clinical medical treatment, especially Radiology, and nuclear accidents. It is especially suitable for patients with radiotherapy, prevention and prevention. The treatment of cognitive impairment caused by radiation, such as memory loss, learning ability loss, has great value of promotion.
【技术实现步骤摘要】
淫羊藿提取物在制备治疗辐射后脑神经损伤及认知障碍的药物中的用途
本专利技术属于医药
，特别涉及淫羊藿提取物在制备治疗辐射后脑神经损伤及认知障碍的药物中的用途。
技术介绍
淫羊藿为小檗科植物淫羊藿EpimediumbrevicornumMaxim.、箭叶淫羊藿Epimediumsagiyyatum(Sieb.etZucc.)Maxim、柔毛淫羊藿EpimediumpubescensMaxim、巫山淫羊藿EpimediumwushanenseT.S.Ying或朝鲜淫羊藿EpimediumkoreanumNakai的干燥地上部分。本夏、秋季茎叶繁茂时采割，除去粗梗及杂质，晒干或阴干。淫羊藿是我国传统的补肾中药，《本草纲目》上记载有“益精气、坚筋骨、补腰膝、强心力”等作用，2010版《中国药典》上记载有“补肾阳、强筋骨、祛风湿”等作用。淫羊藿主要含有黄酮、多糖、木脂素、生物碱等化学成分。现代药理研究也表明淫羊藿具有良好的补肝肾、强筋骨、祛风湿、抗氧化、抗衰老、提高免疫力、抑制肿瘤和保护心脑血管系统等多方面的药理活性。当前辐射已经成为一个严重的公共健康问题，随着科技的...
【技术保护点】
1.淫羊藿提取物在制备治疗辐射后脑神经损伤及认知障碍的药物中的用途。
【技术特征摘要】
1.淫羊藿提取物在制备治疗辐射后脑神经损伤及认知障碍的药物中的用途。2.如权利要求1所述的淫羊藿提取物在制备治疗辐射后脑神经损伤及认知障碍的药物中的用途，其特征在于，所述淫羊藿提取物包括淫羊藿苷。3.如权利要求2所述的淫羊藿提取物在制备治疗辐射后脑神经损伤及认知障碍的药物中的用途，其特征在于，所述淫羊藿提取物还包括金丝桃苷，朝藿定B，朝藿定C和肌醇。4.如权利要求1所述的淫羊藿提取物在制备治疗辐射后脑神经损伤及认知障碍的药物中的用途，其特征在于，所述...
【专利技术属性】
技术研发人员：彭小春，唐锋儒，黄江荣，王思维，钱锋，
申请(专利权)人：长江大学，
类型：发明
国别省市：湖北,42
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