A novel (I) structured inhibitor of fibroblast growth factor receptor 4 (FGFR4) and its preparation method and application are provided. The compound has strong inhibitory effect on the activity of fibroblast growth factor receptor 4 kinase and high selectivity. It can be widely used in the preparation and treatment of cancer, especially prostate cancer, liver cancer, pancreatic cancer, esophageal cancer, gastric cancer, lung cancer, breast cancer, ovarian cancer, colon cancer, skin cancer and glial mother. Drugs for cell tumors or rhabdomyosarcoma are expected to be developed into a new generation of inhibitors of fibroblast growth factor R4.
【技术实现步骤摘要】
【国外来华专利技术】PCT国内申请,说明书已公开。
【技术保护点】
PCT国内申请,权利要求书已公开。
【技术特征摘要】
【国外来华专利技术】2016.12....
【专利技术属性】
技术研发人员:杨飞,邓海兵,应海燕,喻红平,陈椎,徐耀昌,
申请(专利权)人:上海和誉生物医药科技有限公司,
类型:发明
国别省市:上海,31
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