稠环基氮杂环丁基三唑类衍生物、其制备方法及其在医药上的应用技术

本发明专利技术涉及稠环基氮杂环丁基三唑类衍生物、其制备方法及其在医药上的应用。具体而言，本发明专利技术涉及一种通式(I)所示的新的稠环基氮杂环丁基三唑类衍生物、其制备方法及其含有该衍生物的药物组合物及其作为治疗剂，特别是作为催产素拮抗剂的用途和在制备用于治疗或预防已知或可显示抑制催产素会产生有益效应的疾病或病症的药物中的用途，其中通式(I)的各取代基与说明书中的定义相同。

Polycyclic aza-heterocyclic butyl triazole derivatives, their preparation methods and their applications in medicine

The invention relates to polycyclic aza-heterocyclic butyl triazole derivatives, a preparation method thereof and its application in medicine. Specifically, the present invention relates to a new polycyclic aza-butyl triazole derivative shown in general formula (I), its preparation method, its pharmaceutical composition containing the derivative and its use as a therapeutic agent, in particular as an oxytocin antagonist, and in preparation for the treatment or prevention of known or demonstrable inhibition of oxytocin. Uses in medicines that produce beneficial effects for diseases or diseases, in which the substituents of general formula (I) are identical to those defined in the specification.

【技术实现步骤摘要】
【国外来华专利技术】PCT国内申请，说明书已公开。

【技术保护点】
PCT国内申请，权利要求书已公开。

【技术特征摘要】
【国外来华专利技术】2016.12....

【专利技术属性】
技术研发人员：李心，何威，王斌，张志高，贺峰，陶维康，
申请(专利权)人：江苏恒瑞医药股份有限公司，上海恒瑞医药有限公司，
类型：发明
国别省市：江苏,32